Publicaciones
2018
- Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure Fernando J Sánchez-Valdéz, Angel Padilla, Wei Wang, Dylan Orr, Rick L Tarleton. eLife 2018;7:e34039 doi: 10.7554/eLife.34039
2017
- Epidemiological modeling of Trypanosoma cruzi: Low stercorarian transmission and failure of host adaptive immunity explain the frequency of mixed infections in humans. Tomasini N, Ragone PG, Gourbière S, Aparicio JP, Diosque P . PLoS Comput Biol. 2017 May 8;13(5):e1005532. doi: 10.1371/journal.pcbi.1005532.
- Phylogenomics of Trypanosoma cruzi: Few evidence of TcI/TcII mosaicism in TcIII challenges the hypothesis of an ancient TcI/TcII hybridization.Tomasini N, Diosque P. Infection Genetics and Evolution. 2017 Jun;50:25-27. doi: 10.1016/j.meegid.2017.02.010.
- Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal región. Díaz Lozano IM, De Pablos LM, Longhi SA, Zago MP, Schijman AG, Osuna A. Sci Rep. 2017 Mar 15;7:44451. doi: 10.1038/srep44451
- Correction: Methodological approach to the ex vivo expansion and detection of T. cruzi-specific T cells from chronic Chagas disease patients. Acevedo GR, Longhi SA, Bunying A, Sabri N, Atienza A, Zago MP, Santos R, Judkowski VA, Pinilla C, Gómez KA. PLoS One. 2017 Aug 31;12(8):e0184467. doi: 10.1371/journal.pone.0184467
- Gene Expression Profiling and Functional Characterization of Macrophages in Response to Circulatory Microparticles Produced during Trypanosoma cruzi Infection and Chagas Disease. Chowdhury IH, Koo SJ, Gupta S, Liang LY, Bahar B, Silla L, Nuñez-Burgos J, Barrientos N, Zago MP, Garg NJ. Journal of Innate Immunity. 2017;9(2):203-216. doi: 10.1159/000451055.
- New insights into enterocin CRL35: mechanism of action and immunity revealed by heterologous expression in Escherichia coli. Barraza DE, Ríos Colombo NS, Galván AE, Acuña L, Minahk CJ, Bellomio A, Chalón MC. Molecular Microbiology. 2017 Jul 10. doi: 10.1111/mmi.13746.
- Influence of a tropical grass ( Brachiaria brizantha cv. Mulato ) as cover crop on soil biochemical properties in a degraded agricultural soil. Pérez Brandan, Carolina ; Chavarría, Diego; Huidobro, Jorgelina; Meriles, José M.; Pérez Brandan, Cecilia; Vargas Gil, Silvinauropean Journal Of Soil Biology; Lugar: Paris; Año: 2017 vol. 83 p. 84 - 90.
- Effects of IFN-gamma coding plasmid supplementation in the immune response and protection elicited by Trypanosoma cruzi attenuated parasites Cecilia Pérez Brandán; Andrea C. Mesias; Cecilia Parodi; Rubén O. Cimino; Carolina Pérez Brandán; Patricio Diosque; Miguel Angel Basombrío. BMC Infectious Diseases. Londres; Año: 2017.
- Introgression of the Kinetoplast DNA: An Unusual Evolutionary Journey in Trypanosoma cruzi. Tomasini, N. Current Genomics 19(2): 133-139
- Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using Clustered Regularly Interspaced Short Palindromic Repeats–CRISPR Associated Protein 9 Ribonucleoproteins. Lia Carolina Soares Medeiros, Lilith South, Duo Peng, Juan M. Bustamante, Wei Wang, Molly Bunkofske, Natasha Perumal, Fernando Sanchez-Valdez, Rick L. Tarleton. MBio. 2017 Nov 7;8(6). pii: e01788-17. doi: 10.1128/mBio.01788-17
- Identification Of A Novel 1,4,8-Triazaphenanthrene derivative as a neuroprotectant for dopamine neurons vulnerable in Parkinson's Disease. Le Douaron G, Ferrié L, Sepulveda-Díaz JE, Séon-Méniel B, Acuña, L, raisman-Vozari R, Michel PP, Figadére B. Chemical Neuroscience (2017). ISSN: 1948-7193.
- Exploiting the therapeutic potential of Ready-To-Use Drugs: repurposing antibiotics against amyloid aggregation in Neurodegenerative Diseases. Sergio Benjamin Socias, Florencia Gonzalez-Lizarraga, Cesar Avila, Cecilia Vera, Leonardo Acuña, Julia Sepúlveda-Diaz, Elaine Del-Bel, Rita Raisman-Vozari. Progress in Neurobiology. 2017. ISSN: 0301-0082.
- Total Leishmania antigens with Poly(I:C) induce Th1 protective response. Sanchez MV, Eliçabe RJ, Di Genaro MS, Germano MJ, Gea S, Garcia Bustos MF, Salomon MC, Scodeller EA, Cargnelutti DE. Parasite Immunology 2017; e12491.
- American Cutaneous Leishmaniasis in Infancy and Childhood. Alberto E. Paniz-Mondolfi, Carolina Talhari, María F. García Bustos, Tamara Rosales, Wilmer E. Villamil-Gomez, Marilianna Marquez, Alexandra M. Pérez Alvarez, Alejandra I. Tálamo Sánchez, and Alfonso J. Rodriguez-Morales. International Journal of Dermatology. 2017, 56, 1328–1341.
2016
- Clinical and epidemiological features of leishmaniasis in northwestern-Argentina through a retrospective analysis of recent case. Bustos MF, González-Prieto G, Ramos F, Mora MC, Hashiguchi Y, Parodi C, Basombrío MA, Moreno S, Monroig S, Beckar J, Jaime D, Sajama J, Yeo M, Marco JD, Locatelli FM, Barrio A. s. Acta Trop154: 125–132. 2016
- TcI Isolates of Trypanosoma cruzi Exploit the Antioxidant Network for Enhanced Intracellular Survival in Macrophages and Virulence in Mice. Zago MP, Hosakote YM, Koo SJ, Dhiman M, Piñeyro MD, Parodi-Talice A, Basombrio MA, Robello C, Garg NJ. Infection and Inmunity. Junio 2016.
- American tegumentary leishmaniasis: T-cell differentiation profile of cutaneous and mucosal forms-co-infection with Trypanosoma cruzi. Parodi C, García Bustos MF, Barrio A, Ramos F, González Prieto AG, Mora MC, Baré P, Basombrío MA, de Elizalde de Bracco MM.Medical Microbiology and Immunology. Agosto 2016.
- Epidemiology of American Tegumentary Leishmaniasis and Trypanosoma cruzi Infection in the Northwestern Argentina. Hoyos CL, Cajal SP, Juarez M, Marco JD, Alberti D'Amato AM, Cayo M, Torrejón I, Cimino RO, Diosque P, Krolewiecki AJ, Nasser JR, Gil JF. Biomed. 2016.
- The TcTASV proteins are novel promising antigens to detect active Trypanosoma cruzi infection in dogs. Floridia-Yapur N, Monje Rumi M, Ragone P, Lauthier JJ, Tomasini N, Alberti D'Amato A, Diosque P, Cimino R, Marco JD, Barroso P, Sanchez DO, Nasser JR, Tekiel V. Parasitology. Septiembre 2016.
- Gallbladder cancer: South American experience.Arroyo GF, Gentile A, Parada LA. Chinese Clinical Oncology. 2016 Oct;5
- Exposure to Inorganic Arsenic Is Associated with Increased Mitochondrial DNA Copy Number and Longer Telomere Length in Peripheral Blood. Ameer SS, Xu Y, Engström K, Li H, Tallving P, Nermell B, Boemo A, Parada LA, Peñaloza LG, Concha G, Harari F, Vahter M, Broberg K.Frontiers in Cell and Developmental Biology. Agosto 2016
- Lck/PLCγ control migration and proliferation of interleukin (IL)-2-stimulated T cells via the Rac1 GTPase/glycogen phosphorylase pathway. Llavero F, Artaso A, Lacerda HM, Parada LA, Zugaza JL. Cellular Signalling. Noviembre 2016 Noviembre.
- PLAGL1: an important player in diverse pathological processes. Vega-Benedetti AF, Saucedo C, Zavattari P, Vanni R, Zugaza JL, Parada LA. Journal of Applied Genetics. Junio 2016
- S-Nitrosylation Proteome Profile of Peripheral Blood Mononuclear Cells in Human Heart Failure.Koo SJ, Spratt HM, Soman KV, Stafford S, Gupta S, Petersen JR, Zago MP, Kuyumcu-Martinez MN, Brasier AR, Wiktorowicz JE, Garg NJ. International Journal of Proteomics. 2016.
- Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease. Garg NJ, Soman KV, Zago MP, Koo SJ, Spratt H, Stafford S, Blell ZN, Gupta S, Nuñez Burgos J, Barrientos N, Brasier AR, Wiktorowicz JE. PLos Neglected Tropical Diseases. 2016.
- Characterization and genetic diversity of pepper (Capsicum spp) parents and interspecific hybrids. Costa MP, do Rêgo MM, da Silva AP, do Rêgo ER, Barroso PA. Genetic Molecular Research. Mayo 2016.
- Accuracy of five serologic tests for the follow up of Strongyloides stercoralis infection. Buonfrate D; Sequi M; Mejia R; Cimino R; Krolewiecki Aj; Albonico M; Degani M; Tais S; AnghebenA; Requena-Mendez A; Muñoz J; Nutman Tb; Bisoffi Z . Plos neglected tropical diseases. , San Francisco: Public Library Science 2015 - vol. 9, n° 2, p. 1-12. ISSN 1935-2735
- Progressive reduction of circulating B lymphocytes in patients with X-linked lymphoproliferative disease (XLP). Baré Patricia; Parodi Cecilia; Malbrán Alejandro; Elizalde de Bracco M Marta British Journal of Haematology. , Londres: Wiley-Blackwell Publishing, INC, 2016
- Activated Kinase pathway controls retinoblastoma protein phosphorylation and E2F transcription factor activation in B Lymphocytes. Zaldua N.; Llavero F.; Artaso A.; Galvez P.; Lacerda H.M.; Parada L.A.; Zugaza J.L. . Rac1/p21- Febs journal. , Londres: Wiley-Blackwell Publishing, INC, 2016 - . vol. 283, n° 4, p. 647-661. ISSN 1742-464X.
- Diagnosis of Strongyloides stercoralis:Detection of parasite-derived DNA in Urine. Lodh, N; Caro, N; Soiefer, S; Scott, A; Krolewiecki, A; Shiff, C. Acta Trópica. 2016 – Vol 163,pages 9-13.
- Spatial spread of dengue in a non-endemic tropical city in northern Argentina. Gil, JF; Palacios, M; Krolewiecki, AJ; Cortada, P; Flores, R; Jaime, C; Arias, L; Villalpando, C; Alberti D´Amato, AM; Nasser, Rr; Aparicio, JP. Acta Trópica. 2016 - . vol. 158, p. 24-31.
- Systematic review and meta-analysis of the pharmacokinetics of benznidazole in the treatment of Chagas Disease. Wiens MO; Kanters S; Mills E; Peregrina Lucano AA; Gold S; Ayers D; Ferrero L; Krolewiecki A. Antimicrobial agents and chemotherapy. , Washington: American Society of Microbiology, 2016 - Vol. 60, n° 12, p. 7035-7042.
- High prevalence of Strongyloides stercoralis in school-aged children in a rural highland of north-western Ethiopia: the role of intensive diagnostic workup. Amor A; Rodriguez E; Saugar JM; Arroyo A; Lopez-Quintana B; Aberra B; Yimer M; Yizengaw E; Zewdie D; Ayehubizu Z; Hailu T; Mulu W; Echazú A; Krolewiecki AJ; Aparicio P; Herrador Z; Anegagrie M; Benito A. Parasites and vectors. Londres: Biomed Central LTD, 2016 - Vol. 9, n° 617, p. 1-8
- Lupus Eritematoso Tumidus y Leishmaniasis: a propósito de un caso. Monroig, S; Garcia Bustos, MF; González Prieto, G; Ramos, F; Segura, G; Barrio, AB .
- Revista de la federación argentina de sociedades de otorrinolaringología. , Buenos Aires: Federación Argentina de Sociedades de Otorrinolaringología, 2016- Vol. 23, n° 3, p. 72-74.
- Gene Expression Profiling and Functional Characterization of Macrophages in Response to Circulatory Microparticles Produced during Trypanosoma cruzi Infection and Chagas Disease. Chowdhury, I.H.; Koo, S.J.; Gupta, S.; Liang, I.L.; Bahar, B. ; Silla, L.; Nuñez Burgos,J.; Barrientos, N.; Zago, M.P.; Garg, N.J Journal of innate immunity 2016 -
- Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways. Flávia V. Santa-Cecília, Benjamin Socias, Mohand O. Ouidja, Julia E. Sepulveda-Diaz, Leonardo Acuña, Rangel L. Silva, Patrick P. Michel, Elaine Del-Bel, Thiago M., Rita Raisman-Vozari. Neurotoxicity Research. Volumen 29, Tomo 4, págs 447-459. Enero 2016.
2015
- More about miltefosine in the treatment of mucosal leishmaniasis. García Bustos MF, Barrio A, Basombrío MA.Medicina (Buenos Aires). 2016.
- Possible Reservoirs and Vectors. Barroso Paola A, Marco Jorge D., Locatelli Fabricio M., Cardozo Rubén M., Hoyos Carlos L., Mora María C., García Bustos María F., Lopez-Quiroga Inés, Mimori Tatsuyuki, Gentile Alberto G., Barrio Alejandra B., Korenaga Masataka, Hashiguchi Yoshihisha, Basombrío Miguel A. American Journal of Tropical Medicine & Hygiene March 2015.
- Detección de Trypanosoma cruzi en tejido y sangre murina por PCR convencional y en tiempo real. Davies C, Poma RH, Cardozo RM, Mora MC, Ramos F, Rajal VB, Basombrío MA. 2014.. Acta Bioquím. Clín. Latinoam. vol.48 no.4.
- Trypanosoma cruzi diversity in the Gran Chaco: mixed infections and differential host distribution of TcV and TcVI. Monje-Rumi MM, Brandán CP, Ragone PG, Tomasini N, Lauthier JJ, Alberti D'Amato AM, Cimino RO, Orellana V, Basombrío MA, Diosque P.. Infect Genet Evol. 2015 Jan
- Multilocus sequence typing approach for a broader range of species ofLeishmania genus: Describing parasite diversity in Argentina. Marco JD, Barroso PA, Locatelli FM, Cajal SP, Hoyos CL, Nevot MC, Lauthier JJ,Tomasini N, Juarez M, Estévez JO, Korenaga M, Nasser JR, Hashiguchi Y, Ruybal P.. Infect Genet Evol. 2015 Marzo
- Evolution of Trypanosoma cruzi: clarifying hybridisations, mitochondrial introgressions and phylogenetic relationships between major lineages. Tomasini N, Diosque P.. Mem Inst Osw Cruz. 2015.
- Analytical Validation of Quantitative Real-Time PCR Methods for Quantification of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients. Ramírez Jc; Cura Ci; Da Cruz Moreira O; Lages-Silva E; Juiz N; Velázquez E; Ramírez Jd; Alberti A; Pavia P; Flores-Chávez Md; Muñoz-Calderón A; Pérez-Morales D; Santalla J; Marcos Da Matta Guedes P; Peneau J; Marcet P; Diosque P; Yadón Ze; Schijman AG . Journal Of Molecular Diagnostics. 2015 - . ISSN 1525-1578
- Angiogenic effects of ionic dissolution products released from a boron-doped 45S5 bioactive glass. Journal of materials chemistry. Haro Durand L; Vargas GE; Vera Mesones R; Romero M; Porto López JM; Boccaccini Ar; Zago Mp; Baldi A; Gorustovich A ., Cambridge: Royal Soc Chemistry, 2015 - . vol. 2015, p. 1142-1148. ISSN 0959-9428.
- Clinical and epidemiological features of leishmaniasis in northwestern-Argentina through a retrospective analysis of recent cases. Garcia Bustos Mf; Gonzalez-Prieto G; Ramos F; Mora Mc; Hashiguchi Y; Parodi C; Basombrío MA; Moreno S; Monroig S; Beckar J; Jaime D; Sajama J; Yeo M; Marco Jd; Locatelli FM; Barrio AB . Acta Trópica. , Amsterdam: Elsevier Science BV, 2015 - . vol. 154, p. 125-132. ISSN 0001-706X.
2014
- Trypanosoma cruzi diversity in the Gran Chaco: Mixed infections and differential host distribution of TcV and TcVI. María M. Monje-Rumi , Cecilia Pérez Brandán ,Paula G. Ragone, Nicolás Tomasini , Juan J. Lauthier, Anahí M. Alberti D’Amato , Rubén O. Cimino, Viviana Orellana , Miguel A. Basombrío, Patricio Diosque. Infection, Genetics and Evolution. 29 , pág 53–59. Noviembre 2014.
- A monoallelic deletion of the TcCRT gene increases the attenuation of a culturedTrypanosoma cruzi strain, protecting against an in vivo virulent challenge. Sánchez-Valdéz FJ, Pérez Brandán C, Ramírez G, Uncos AD, Zago MP, Cimino RO, Cardozo RM, Marco JD, Ferreira A, Basombrío MA. . PLoS Negl Trop Dis 8(2):e2696. 2014.
- The isolation and molecular characterization of Leishmania spp. from patients with American tegumentary leishmaniasis in northwest Argentina. Locatelli FM, Cajal SP, Barroso PA, Lauthier JJ, Mora MC, Juarez M, Kato H, Nasser JR, Korenaga M, Hashiguchi Y, Marco JD. . Acta Trop 131:16-21. 2014.
- Gene-deleted live-attenuated Trypanosoma cruzi parasites as vaccines to protect against Chagas disease. Fernando J. Sánchez Valdez, Cecilia Perez Brandan, Arturo Ferreira and Miguel Angel Basombrío Expert Reviews. Vaccines Early online, 1–17 (2014)
- Evaluation of recombinant antigens of Trypanosoma cruzi to diagnose infection in naturally infected dogs from Chaco region, Argentina. Floridia-Yapur N, Vega-Benedetti AF, Rumi MM, Ragone P, Lauthier JJ, Tomasini N, d'Amato AM, Lopez-Quiroga I, Diosque P, Marcipar I, Nasser JR, Cimino RO.. Parasite Immunol. 2014 Dec;36(12):694-9.
- Optimized multilocus sequence typing (MLST) scheme for Trypanosoma cruzi. Diosque P, Tomasini N, Lauthier JJ, Messenger LA, Monje Rumi MM, Ragone PG, Alberti-D'Amato AM, Pérez Brandán C, Barnabé C, Tibayrenc M, Lewis MD, Llewellyn MS, Miles MA, Yeo M. PLoS Negl Trop Dis. 2014 Aug 28;8(8):e3117.
- Preponderant clonal evolution of Trypanosoma cruzi I from Argentinean Chaco revealed by Multilocus Sequence Typing (MLST).Tomasini N, Lauthier JJ, Monje Rumi MM, Ragone PG, Alberti D'Amato AM, Brandán CP, Basombrío MA, Diosque P. Infect Genet Evol. 2014 Oct;27:348-54.
- How often do they have sex? A comparative analysis of the population structure of seven eukaryotic microbial pathogens. Tomasini N, Lauthier JJ, Ayala FJ, Tibayrenc M, Diosque P.. PLoS One. 2014 Jul 23;9(7):e103131.
2013
- 1-42 B-amyloid peptide (AB1-42) requires PDK1/nPKCs/Rac 1 pathway to induce neuronal death. Manterola L.; Hernando-Rodriguez M.; Ruiz A.; Apraiz A.; Arrizabalaga O.; Vellon L.; Alberdi E.; Cavaliere F.; Lacerda H.M.; Jimenez S.; Parada L.A.; Matute C.; Zugaza J.L ., Translational psychiatry .Londres: NATURE PUBLISHING GROUP, 2013 - vol. 3, n° 1, p. 219-219.
- Health Response against Strongyloides stercoralis : Time to Look at Soil-Transmitted Helminthiasis in Full. Krolewiecki AJ; Lammie, P; Jacobson, J; Gabrielli, AF; Levecke, B; Socias M; Arias, L; Sosa, N; Abraham, D; Cimino, R; Echazú, A; Crudo, F; Vercruysse, J; Albonico, M . A Public. Plos Neglected Tropical Diseases. , San Francisco: PUBLIC LIBRARY SCIENCE, 2013 - . vol. 7, n° 5, p. 1-7.
- Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease. Gupta, S; Wan, X; Zago, MP; Martinez Sellers, V; Silva, TS; Assiah, D; Dhiman, M; Nuñez, S; Petersen,JR; Vazquez-Chagoyán, JC; Estrada-Franco, JG; Garg, NJ . Plos Neglected Tropical Diseases. , San Francisco: PUBLIC LIBRARY SCIENCE 2013 - . vol. 7, n° 1, p. 1-10.
- ATP Antagonizes Thrombin Induced Signal Transduction through 12(S)-HETE and cAMP. Burzaco J.; Conde M.; Parada L.A.; Zugaza J.L.; Dehaye J.P.; Marino A. Plos One. , San Francisco: PUBLIC LIBRARY SCIENCE, 2013 - . vol. 8, p. 67117-67118.
- Benznidazole treatment in chronic children infected withTrypanosoma cruzi: Serological and molecular follow-up of patientsand identification of Discrete Typing Units M.M. Monje Rumi, C. Pérez Brandán, J.F. Gil, A.M. Alberti Damato, P.G. Ragone, J.J. Lauthier, N.Tomasini, R.O. Cimino, V. Orellana, C.D. Lacunza, J.R. Nasser, M.A. Basombrío, P. Diosque. Acta Trópica. Amsterdam: ELSEVIER SCIENCE BV, 2013 - . vol. 128, n° 1, p. 130-136.
- Combined Fluorescent-Chromogenic In Situ Hybridization for Identification and Laser Microdissection of Interphase Chromosomes. Paz N.; Zabala A.; Royo F.; Garcí-Orad A.; Zugaza J,L.; Parada L.A. Plos one , San Francisco: PUBLIC LIBRARY SCIENCE, 2013 - . vol. 8, n° 4, p. 60238-60238.
- Diagnóstico de infección por Trypanosoma cruzi en centros de atención primaria de Salta, Argentina. Olga Sánchez Negrette; María Concepción Monteros; Carolina Davies; Mario Oscar Zaidenberg. Acta Bioquímica Clínica Latinoamericana. , Buenos Aires: Federación Bioquímica Provincia Buenos Aires, 2013 - . vol. 47, n° 4, p. 701-707.
- Estimation ofHIV-testing rates to maximize early diagnosis-derived benefits at the individual and population level. Dilernia DA; Monaco DC; Cesar C; Krolewiecki AJ; Friedman SR; Cahn P; Salomon H. Plos One. , San Francisco: Public Library Science, 2013 - . vol. 8, n° 1, p. 1-13.
- Innate, immune, responses and antioxidant/oxidant imbalance are major determinants of human Chagas disease.Dhiman, M; Coronado, Ya; Vallejo, CK; Petersen, JR; Ejilemele, A; Nuñez, S; Zago, MP; Spratt, H; Garg NJ. Plos neglected tropical diseases. , San Francisco: Public Library Science, 2013 - . vol. 8, p. 2364-2364.
- MLSTest: Novel software for multi-locus sequence data analysis in eukaryotic organisms. Nicolás Tomasini; Juan José Lauthier; Martin S. Llewellyn; Patricio Diosque .Infection, genetics and evolution. , Amsterdam: Elsevier Science BV, 2013 - . vol. 20, p. 188-196.
- Restricted outbreak of American tegumentary leishmaniasis with high microfocal transmission. American journal of tropical medicine and higiene. Alejandro J. Krolewiecki; Jose F. Gil; Marcelo Quipildor; Silvana P. Cajal; Carlos Pravia; Marisa Juarez; Carlos Villalpando; Fabricio M. Locatelli; Mariana Chanampa; Gabriela Castillo; Marı´A F. Oreste; Carlos L. Hoyos; Vanesa Negri; Julio R. Nasser. 2013 - . vol. 88, n° 3, p. 578-582.
- Trypanosoma cruzi carrying a monoallelic deletion of the calreticulin (TcCRT) gene are susceptible to complement mediated killing and defective in their metacyclogenesis.Sánchez Valdéz Fernando Javier; Cecilia Pérez Brandán; María Paola Zago; Carlos Labriola; Arturo Ferreira; Miguel Angel Basombrío . Molecular immunology , Amsterdam: PERGAMON-ELSEVIER SCIENCE LTD, 2013 - . vol. 53, p. 198-205.
2012
- Trypanosoma cruzi Carrying a Monoallelic Deletion of the Calreticulin (TcCRT) gene are Susceptible to Complement Mediated Killing and Defective in their Metacyclogenesis. Fernando J. Sánchez Valdéz, Cecilia Pérez Brandán, M. Paola Zago, Carlos Labriola, Arturo Ferreira, Miguel Ángel Basombrío. Molec. Immunol., 2012. 53 (3): p. 198-205
- Biological behavior of different Trypanosoma cruzi isolates circulating in an endemic area for Chagas disease in the Gran Chaco region of Argentina. Ragone, Paula Gabriela; Perez Brandan, Cecilia; Padilla Marcelo A; Monje Rumi, Maria Mercedes; Lauthier, Juan José; Alberti D'amato, Anahi A; Tomasini, Nicolas; Cimino, Rubén O; Romero Nm; Portelli Marcela; Nasser Julio R; Basombrio, Miguel A; Diosque, Patricio. Acta tropica. , Amsterdam: ELSEVIER SCIENCE BV, 2012 - . p. 1-6.
- Candidate targets for Multilocus Sequence Typing of Trypanosoma cruzi: validation using parasite stocks from the Chaco Region and a set of reference strains. Lauthier Jj, Tomasini N, Barnabé C, Rumi Mm, D'amato Am, Ragone Pg, Yeo M, Lewis Md, Llewellyn Ms, Basombrío Ma, Miles Ma, Tibayrenc M, Diosque P. Infection,genetics and evolution. : ELSEVIER SCIENCE BV, 2012 - . p. 350-358.
- Cardiac-oxidized antigens are targets of immune recognition by antibodies and potential molecular determinants in chagas disease pathogenesis. Dhiman M; Zago Mp; Nunez S; Amoroso A; Rementeria H; Dousset P; Nunez Burgos F; Garg Nj .Plos one. , San Francisco: PUBLIC LIBRARY SCIENCE, 2012 - . vol. 7, n° 1, p. 1-13.
- Comparación de la eficiencia de extracción de ácidos nucleicos utilizando distintos kits comerciales. Efecto de las sustancias inhibidoras. H.R. Poma; C. Davies; D. Gutiérrez Cacciabue; M.C. Mora; M.A. Basombrío; V.B. Rajal. Revista Argentina de Microbiologia.. , Buenos Aires: ASOCIACION ARGENTINA MICROBIOLOGIA, 2012 - . vol. 44, p. 144-149.
- Controlling cytoplasmic c-Fos controls tumor growth in the peripheral and central nervous system. Neurochemical research. Germán A. Gil; David C. Silvestre; Nicolás Tomasini; Daniela F. Bussolino; Beatriz L. Caputto. , New York: SPRINGER/PLENUM PUBLISHERS, 2012 - . vol. 37, n° 6, p. 1364-1371.
- Development of a new platform for neglected tropical disease surveillance. International journal for parasitology. Lammie, P; Moss Dm; Brook Goodhew E; Hamlin K; Krolewiecki A; West Sk; Priest Jw.: ELSEVIER SCI LTD,2012 - . vol. 42, n° 9, p. 797-800.
- Genetically attenuated Trypanosoma cruzi parasites are a potential tool for vaccination approaches. Bioengineered. Perez Brandan Cecilia And Miguel Angel Basombrio : Landes Biosciencia Journals, 2012 - . vol. 1, n° 4, p. 1-5. ISSN 1949-1018
- Geohelmintiasis en el NOA? KROLEWIECKI A . Filariasis y Ascariasis.. Revista médica de salta. , Salta: Círculo Médico de Salta, 2012 - . n° 43, p. 31-36. ISSN 1514-6219
- Instituto de Patología Experimental (IPE): Una Unidad ejecutora UNSa-CONICET. Basombrío MA, Parada LA. Revista de la Facultad de Ciencias de la Salud. , Salta: Facultad de Ciencias de la Salud, 2012- . vol. 1, n° 2, p. 37-41. ISSN 2250-5628
- Leishmania infantum and Human cutaneus Leishmaniasis Argentina. Emerging infectious diseases Alejandra Barrio; Cecilia M. Parodi; Fabricio Locatelli; María C. Mora; Miguel A. Basombrío; Masataka Korenaga; Yoshihisa Hashiguchi; María F. García Bustos; Alberto Gentile; Jorge D. Marco. DOI: http://dx.doi.org/10.3201/eid1802.110924, 2012 - . vol. 18, n° 2, p. 354-355.
- Polymorphism-specific PCR enhances the diagnostic performance of American tegumentary leishmaniasis and allows the rapid identification of Leishmania species from Argentina. Marco Jd; Barroso Pa; Mimori T; Locatelli Fm; Tomatani A; Mora Mc; Cajal Sp; Nasser Jr; Parada La; Taniguchi T; Korenaga M; Basombrío Ma; Hashiguchi Y . Bmc Infectious Diseases. , Londres: BIOMED CENTRAL LTD, 2012 - . Vol. 12, N° 191, P. 1-8.
- Prioritizing CD4 count monitoring in response to ART in resource-constrained settings: a retrospective application of prediction-based classification. Azzoni L; Foulkes As; Liu Y; Li X; Johnson M; Smith C; Kamarulzaman Ab; Montaner J; Mounzer K; Saag M; Cahn P; Cesar C; Krolewiecki A; Sanne I; Montaner Lj Plos medicine. , San Francisco: Public Library Science, 2012 - vol. 9, n° 4, p. 1-11.
- Benznidazole treatment in children infected with Trypanosoma cruzi: serological and molecular follow-up. Monje Rumi Mm; Gil Fj; Alberti D'amato, Am; Perez Brandan, C; Ragone Pg; Lauthier Jj; Tomasini N; Cimino Ro; Orellana V; Lacunza D; Nasser Jr; Basombrío Ma; Diosque P. Acta tropica. , Amsterdam Elsevier Science BV, 2012 - .
- Serum proteomic signature of human chagasic patients for the identification of novel protein biomarkers of disease. Jian-Jun Wen; M. Paola Zago; Sonia Nuñez; Shivali Gupta; Federico Nunez Burgos; Nisha Jain Garg. Molecular & cellular proteomics. : ASBMB, 2012 - . ISSN 1535 9476
2011
Knockout of the dhfr-ts Gene in Trypanosoma cruzi Generates Attenuated Parasites Able to Confer Protection Against a Virulent Challenge. Cecilia M. Perez Brandan, Angel M. Padilla, Dan Xu, Rick L. Tarleton and Miguel A. Basombrio. PLoS Neglected Tropical Diseases, 2011 Dec;5(12):e1418
Immuno-enzymatic evaluation of the recombinant TSSA-II protein of Trypanosoma cruzi in dogs and human sera: a tool for epidemiological studies. Cimino RO, Rumi MM, Ragone P, Lauthier J, D'Amato AA, Quiroga IR, Gil JF, Cajal SP, Acosta N, Juárez M, Krolewiecki A, Orellana V, Zacca R, Marcipar I, Diosque P, Nasser JR. Parasitology. 2011 Jul;138(8):995-1002.
Interest and limitations of Spliced Leader Intergenic Region sequences for analyzing Trypanosoma cruzi I phylogenetic diversity in the Argentinean Chaco. Tomasini, N, Lauthier, JJ, Monje Rumi, MM, Ragone, PG, Alberti D’Amato, A, Pérez Brandan, C, Cura, CI, Schijman, AG, Barnabé, C, Tibayrenc, M, Basombrío, MA, Falla, A, Herrera, C, Guhl, F, Diosque, P. Infect Genet Evol. 2011 Mar;11(2):300-7.
Acute retroviral syndrome and high baseline viral load are predictors of rapid HIV progression among untreated Argentinean seroconverters. Socias, Me; Sued, O; Laufer, N; Lazaro, M; Mingrone, H; Pryluka, D; Remondegui, C; Figueroa, Mi; Cesar, C; Gun, A; Turk, Gabriela; Bouzas, Mb; Kavasery, A; Krolewiecki, A; Perez, H; Salomon; Cahn, P. Journal of the international aids society. , Ginebra: International AIDS Society, 2011 - . vol. 14, p. 1-9. ISSN 1758-2652
Persons from the Caribbean, Central and South America. Journal of acquired immune deficiency syndromes (1999).Fink V; Shepherd B; Cesar C; Krolewiecki A; Wehbe F; Cortes C; Crabtree- Ramirez B; Padgett D; Shafaee M; Schechter M; Gotuzzo E; Bacon M; Mcgowan C; Cahn P; Masys D . Cancer in HIV-Infected. Filadelfia: LIPPINCOTT WILLIAMS & WILKINS, 2011 - . vol. 56, n° 5, p. 467-473.
El rol de tres pruebas de Elisa con antígenos de promastigotes de leishmania braziliensis, l. amazonensis y l. guyanensis en el diagnóstico de Leishmaniasis tegumentaria. Gil, Jf; Hoyos, C; Cimino, Ro; Krolewiecki, Aj; Lopez Quiroga, I; Cajal, Sp; Juarez, M; García Bustos, Mf; Mora, Mc; Marco, Jd; Nasser, Jr. MEDICINA (Buenos Aires), 2011 - vol. 71, n° 5, p. 420-428.
Immunological correlates of cure in the first American Cutaneous Leishmaniasis patient treated by immunotherapy in Argentina. A case report. María Fernanda García Bustos, Alejandra Beatriz Barrio, Cecilia María Parodi Ramoneda, Federico Ramos, María Celia Mora, Jacinto Convit Y Miguel Angel Manuel Basombrío. Investigacion clínica , 2011 - . vol. 52, p. 1-11.
Isolation of fetal liveroval cells in physiologic conditions form their natural niche. Acta gastroenterologica latinoamericana. Torres-Fuenzalida J.; Castronuovo C.; Hidalgo A.; Parada L.A.; Lorenti A. Sociedad Argentina De Gastroenterología, 2011- vol. 41, p. 36-46.
Ivermectin-related adverse clinical events in patients treated for Mansonella ozzardi infections. Krolewiecki AJ; Cajal SP; Villalpando C; Gil JFRevista argentina de Microbiología.. , Buenos Aires: Asociacion Argentina de Microbiologia, 2011 - . vol. 43, n° 1, p. 48-50.
Multilocus Sequence Typing (MLST) for Lineage Assignment and High Resolution Diversity Studies in Trypanosoma cruzi. Yeo M; Mauricio Il; Messenger La; Lewis Md; Llewellyn Ms; Acosta N; Bhattacharyya T; Diosque P; Carrasco Hj; Miles Ma. Plos Neglected Tropical Diseases. : PUBLIC LIBRARY SCIENCE, 2011 - .vol. 11, n° 6, p. 1049-1049.
No reduction of HCV viral load in HIV patients co-infected with HCV genotype 1 during a 30days course of nitazoxanide monotherapy. Laufer N; Abusamra L; Bolcic F; Gun A; Rolón Mj; Pérez H; Krolewiecki A; Salomón H; Quarleri J; Cahn P. Antiviral Research. , Filadelfia: ELSEVIER SCIENCE BV, 2011 - . vol. 92, n° 3, p. 497-499.
Randomized Study Assessing Safety, Tolerability and Efficacy of Simplified LPV/r Maintenance Therapy in HIV Patients on the 1st PI-Based Regimen. Cahn P; Montaner J; Junod P; Patterson P; Krolewiecki A; Andrade- Villanueva J; Cassetti I; Sierra-Madero J; Casiró Ad; Bortolozzi R; Lupo Sh; Longo N; Rampakakis E; Ackad N; Sampalis JS . Pilot. Plos One. , Cambridge: PUBLIC LIBRARY SCIENCE, 2011 - . vol. 6, n° 8, p. 1-7.
Reactividad del antígeno GST-SAPA de Trypanosoma cruzi frente a sueros de pacientes con enfermedad de Chagas y leishmaniasis. Gil J; Cimino R; Lopez Quiroga I; Cajal Sp; Acosta N; Juarez M; Zacca R; Orellana V; Krolewiecki A; Diosque P; Nasser J. Medicina-Buenos Aires. , Buenos Aires 2011 - . vol. 71, n° 2, p. 113-119.
The protein synthesis inhibitors mycalamides A and E have limited susceptibility toward the drug efflux network. Journal of biochemical and molecular toxicology. Venturi, Veronica; Davies, Carolina; Singh, Jonathan A.; Matthews, James H.; Bellows, David S; Northcote, Peter T; Keyzers, Robert A. ; Teesdale-Spittle Paul, New York: John Wiley & Sons Inc, 2011 - . vol. 26, p. 94-100
2010
Inheritance of resistance to pyrethroids in Triatoma infestans, the main Chagas disease vector in South America. Cardozo RM, Panzera F, Gentile AG, Segura MA, Pérez R, Díaz RA, Basombrío MA. Infection Genetics and Evolution. Montpellier: Elsevier Science BV, 2010 - . vol. 10, p. 1174-1178.
Hydroxymethylnitrofurazone is active in a murine model of Chagas' disease. Davies C, Marino Cardozo R, Sánchez Negrette O, Mora MC, Chung MC, Basombrío MA. Antimicrob Agents Chemother. 2010 Sep;54(9):3584-9.
Vaccine development for Chagas Disease. Angel Marcelo Padilla, Cecilia Perez Brandan, Miguel Angel Basombrio. American Trypanosomiasis. ISBN 13: 978-0-12-384876-5. ELSEVIER, 2010.
Urban transmission of American cutaneous leishmaniasis in Argentina: spatial analysis study. Gil JF, Nasser JR, Cajal SP, Juarez M, Acosta N, Cimino RO, Diosque P, Krolewiecki AJ. Am J Trop Med Hyg. 2010 Mar;82(3):433-40.
Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis. Hepatology. Martínez-López N.; Varela-Rey M.; Fernández-Ramos D.; Woodhoo A.; Vázquez-Chantada M.; Embade N.; Espinosa-Hevia L.; Bustamante F.J.; Parada L.A.; Rodriguez M.S.; Lu S.C.; Mato J.M.; Martínez Chantar M.L. .(Baltimore, md.). : John Wiley & Sons Inc, 2010 - . vol. 52, p. 1621-1631.
Functional blockade of á5â1 integrin induces scattering and genomic landscape remodeling of hepatic progenitor cells. VellóN L.; Royo F.; Matthiesen R.; Torres-Fuenzalida J.; Lorenti A.; Parada L.A. .Bmc Cell Biology. Biomed Central Ltd, 2010 - . vol. 11, p. 81-89.
In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds. Adriana M. C. Canavaci; Juan M. Bustamante; Angel M. Padilla; Cecilia M. Perez Brandan; Laura J. Simpson; Dan Xu; Courtney L. Boehlke; Rick L. Tarleton. Plos Neglected Tropical Diseases. : PUBLIC LIBRARY SCIENCE, 2010 -vol. 4, p. 1-13.
Trypanosoma cruzi I genotypes in different geographical regions and transmission cycles based on a microsatellite motif of the intergenic spacer of spliced-leader genes. Cura Ci; Mejía-Jaramillo Am; Duffy T; Burgos Jm; Rodriguero M; Cardinal MV; Kjos S; Gurgel Gonçalves R; Blanchet D; De Pablos LM; Tomasini N; Da Silva A; Russomando G; Cuba Ca; Aznar C; Abate T; Levin Mj; Osuna A; Gürtler Re; Diosque P; Solari A; Triana-Chávez O; Schijman AG. International journal for parasitology. : Elsevier Sci LTD, 2010 - . vol. 2010, n° 14, p. 1599-1607.
Partes de Libro 2010
Vaccine development for Chagas Disease. Angel Marcelo Padilla; Cecilia Perez Brandan; Miguel Angel Basombrío. Elsevier, 2010. p. 827-848. ISBN 978-0-12-384876-5.
2009
Congenital Chagas disease involves Trypanosoma cruzi sub-lineage IId in the northwestern province of Salta, Argentina. Corrales RM; Mora MC; Negrette OS; Diosque P; Lacunza D; Virreira M; Brenière SF; Basombrio MA. Infection, genetics and evolution. : Elsevier Science BV, 2009 - . vol. 9, n° 9, p. 278-282.
Enzymes of the antioxidant network as novel determiners of Trypanozoma Cruzi virulence. International journal for Parasitology . Piacenza, L; M. Paola Zago; Peluffo, G; Alvarez, MN; Kelly, M.K; Wilkinson, S.R.; Basombrío, M.A; Radi, R.ELSEVIER SCI LTD, 2009 - . vol. 13, p. 1455-1464.
Evaluation of high efficiency gene knockout strategies for Trypanosoma cruzi. Xu D, Pérez Brandán C, Basombrío Ma, Tarleton RL. BMC Microbiology. : BioMed Central, 2009 - . vol. 9, n° 90, p. 1-10. ISSN 1471-2180.
Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection. Llewellyn MS; Miles MA; Carrasco HJ; Lewis MD; Yeo M; Vargas J; Torrico F; Diosque P; Valente V; Valente Sa; Gaunt Mw . Plos Pathogens. , Pennsylvania, United States of America: Public Library Science, 2009 - . vol. 5, n° 100, p. 1000410-1000410.
Identificación por PS-PCR de especies de Leishmania y su correlación con características clínicas, epidemiológicas y terapéuticas en Salta, Argentina. Revista Argentina de Salud Pública. Alejandra Barrio; María F. García Bustos; María C. Mora; Cecilia M. Parodi; Federico Ramos; Sonia Moreno; Miguel A. Basombrío . Buenos Aires - Argentina: Ministerio de Salud de la Nación Argentina, 2009 - . vol. 1, n° 1, p. 30-33. ISSN 1852-8724
Protective immunity against Trypanosoma cruzi. Cecilia Parodi, Ángel Marcelo Padilla, Miguel Ángel Basombrío. Memorias do Instituto Oswaldo Cruz. : Fundaco Oswaldo Cruz, 2009 - . p. 288-294.
Suceptibilidad de distintas cepas de ratones a la infección por Leishmania amazonensis. María Alejandra Falú, María Fernanda García Bustos, Cecilia María Parodi Ramoneda, Ema Molina de Raspi, Rubén Marino Cardozo, Rubén Cimino, José Fernando Gil, Jorge Leonario Vasvari, Miguel Angel Basombrío .. Dermatología Argentina. : Asociación Argentina de Dermatología, 2009 - . n° 15, p. 334-339. ISSN 0325-2787
Trypanosoma cruzi: adaptation to its vectors and its hosts. Noireau F; Diosque P; Jansen Am. Veterinary Research: EDP SCIENCES S A, 2009 - . p. 26-40.